Dot1 and Histone H3K79 Methylation in Natural Telomeric and HM Silencing

The expression of genes that reside near telomeres is attenuated through telomere position-effect variegation (TPEV). Using a URA3 reporter located at TEL-VIIL of S. cerevisiae, it was demonstrated that the disruptor of telomeric silencing-1 (Dot1) regulates TPEV by catalyzing the methylation of H3K...

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Hauptverfasser: Takahashi, Yoh-Hei, Schulze, Julia M., Jackson, Jessica, Hentrich, Thomas, Seidel, Chris, Jaspersen, Sue L., Kobor, Michael S., Shilatifard, Ali
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3085244/
https://ncbi.nlm.nih.gov/pubmed/21474073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.03.006
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