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Inhibition of gene-specific repair of alkylation damage in cells depleted of poly(ADP-ribose) polymerase.

The role of the enzyme poly(adenosine diphosphate-ribose) polymerase (PADPRP) in DNA repair at the level of the gene was investigated with human HeLa cells in which PADPRP antisense transcripts are inducible with dexamethasone. After such induction, the cellular content of PADPRP is reduced by 90%....

詳細記述

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書誌詳細
主要な著者: Stevnsner, T, Ding, R, Smulson, M, Bohr, V A
フォーマット: Artigo
言語:Inglês
出版事項: 1994
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC308509/
https://ncbi.nlm.nih.gov/pubmed/7984410
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