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Inhibition of poly(ADP-ribose)polymerase-1 and DNA repair by uranium

Uranium has radiological and non-radiological effects within biological systems and there is increasing evidence for genotoxic and carcinogenic properties attributable to uranium through its heavy metal properties. In this study, we report that low concentrations of uranium (as uranyl acetate; <1...

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Publicado en:Toxicol Appl Pharmacol
Autores principales: Cooper, Karen L., Dashner, Erica J., Tsosie, Ranalda, Cho, Young Mi, Lewis, Johnnye, Hudson, Laurie G.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4718819/
https://ncbi.nlm.nih.gov/pubmed/26627003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.11.017
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