Neonatal asphyxia induces the nitration of cardiac myosin light chain 2 (MLC2) which is associated with cardiac systolic dysfunction

BACKGROUND: Hypoxia followed by reoxygenation (H-R) observed during perinatal asphyxia is a serious complication with a high mortality and morbidity rate which may cause adverse cardiovascular effects in neonates. Our aim was to determine if oxidative stress related to H-R induces peroxynitrite-depe...

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Hlavní autoři: Doroszko, Adrian, Polewicz, Dorota, Cadete, Virgilio J.J., Sawicka, Jolanta, Jones, Michelle, Szczesna-Cordary, Danuta, Cheung, Po-Yin, Sawicki, Grzegorz
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084583/
https://ncbi.nlm.nih.gov/pubmed/20386496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/SHK.0b013e3181e14f1d
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