Ischemia/reperfusion-induced myosin light chain 1 phosphorylation increases its degradation by matrix metalloproteinase-2

Degradation of myosin light chain 1 (MLC1) by matrix metalloproteinase-2 (MMP-2) during myocardial ischemia/reperfusion (I/R) injury has been established. However, the exact mechanisms controlling this process remain unknown. I/R increases the phosphorylation of MLC1, but the consequences of this mo...

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Detalhes bibliográficos
Main Authors: Cadete, Virgilio J. J., Sawicka, Jolanta, Jaswal, Jagdip, Lopaschuk, Gary D., Schulz, Richard, Szczesna-Cordary, Danuta, Sawicki, Grzegorz
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3377847/
https://ncbi.nlm.nih.gov/pubmed/22564771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2012.08622.x
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