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Identification of a β-lactamase inhibitory protein variant that is a potent inhibitor of Staphylococcus PC1 β-lactamase

The β-lactamase inhibitory protein (BLIP) binds and inhibits a diverse collection of class A β-lactamases. Widespread resistance to β-lactam antibiotics currently limits treatment strategies for Staphylococcus infections. The goal of this study was to determine the binding affinity of BLIP for S. au...

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Autors principals: Yuan, Ji, Chow, Dar-Chone, Huang, Wanzhi, Palzkill, Timothy
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081586/
https://ncbi.nlm.nih.gov/pubmed/21238457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.01.014
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