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Fine mapping of the sequence requirements for binding of β-lactamase inhibitory protein (BLIP) to TEM-1 β-lactamase using a genetic screen for BLIP function
β-lactamase inhibitory protein (BLIP) binds and inhibits a diverse collection of class A β-lactamases with a wide range of affinities. Alanine-scanning mutagenesis was previously performed to identify the amino acid sequence requirements of BLIP for binding the TEM-1, SME-1, SHV-1 and Bla1 β-lactama...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2728291/ https://ncbi.nlm.nih.gov/pubmed/19389404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.04.028 |
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