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Structural Insight into the Kinetics and ΔCp of Interactions between TEM-1 β-Lactamase and β-Lactamase Inhibitory Protein (BLIP)

In a previous study, we examined thermodynamic parameters for 20 alanine mutants inβ-lactamase inhibitory protein (BLIP) for binding to TEM-1 β-lactamase. Here we have determined the structures of two thermodynamically distinctive complexes of BLIP mutants with TEM-1 β-lactamase. The complex BLIP Y5...

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Bibliografiske detaljer
Main Authors: Wang, Jihong, Palzkill, Timothy, Chow, Dar-Chone
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610523/
https://ncbi.nlm.nih.gov/pubmed/18840610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804089200
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