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Structural Insight into the Kinetics and ΔCp of Interactions between TEM-1 β-Lactamase and β-Lactamase Inhibitory Protein (BLIP)
In a previous study, we examined thermodynamic parameters for 20 alanine mutants inβ-lactamase inhibitory protein (BLIP) for binding to TEM-1 β-lactamase. Here we have determined the structures of two thermodynamically distinctive complexes of BLIP mutants with TEM-1 β-lactamase. The complex BLIP Y5...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2610523/ https://ncbi.nlm.nih.gov/pubmed/18840610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804089200 |
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