Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.
We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that requires positioning of a pair of the gapped duplexes in a configuration that resembles the intgration inter...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1994
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| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8152908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.6.1037 |
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