Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that requires positioning of a pair of the gapped duplexes in a configuration that resembles the intgration inter...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1994
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307927/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8152908/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/22.6.1037
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