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Intermolecular disintegration and intramolecular strand transfer activities of wild-type and mutant HIV-1 integrase.

We report the activities of HIV integrase protein on a novel DNA substrate, consisting of a pair of gapped duplex molecules. Integrase catalyzed an intermolecular disintegration reaction that requires positioning of a pair of the gapped duplexes in a configuration that resembles the intgration inter...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mazumder, A, Engelman, A, Craigie, R, Fesen, M, Pommier, Y
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1994
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC307927/
https://ncbi.nlm.nih.gov/pubmed/8152908
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