Targeted Therapy of VEGFR2 and EGFR Significantly Inhibits Growth of Anaplastic Thyroid Cancer in an Orthotopic Murine Model

PURPOSE: Anaplastic thyroid carcinoma (ATC) is one of the most lethal human cancers with a median survival of 6 months. The inhibition of epidermal growth factor receptor (EGFR) alone, or with vascular endothelial growth factor receptor2 (VEGFR2), represents an attractive approach for treatment of A...

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Hlavní autoři: Gule, Maria K., Chen, Yunyun, Sano, Daisuke, Frederick, Mitchell J., Zhou, Ge, Zhao, Mei, Milas, Zvonimir L., Galer, Chad E., Henderson, Ying C., Jasser, Samar A., Schwartz, David L., Bankson, James A., Myers, Jeffrey N., Lai, Stephen Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3079006/
https://ncbi.nlm.nih.gov/pubmed/21220477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-2762
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