Targeted molecular therapy of head and neck squamous cell carcinoma with the tyrosine kinase inhibitor vandetanib in a mouse model

BACKGROUND: We investigated the effects of vandetanib, an inhibitor of vascular endothelial growth factor receptor 2 (VEGFR-2) and epidermal growth factor receptor (EGFR), alone and in combination with paclitaxel in an orthotopic mouse model of human head and neck squamous cell carcinoma (HNSCC). ME...

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Detalhes bibliográficos
Main Authors: Sano, Daisuke, Fooshee, David R., Zhao, Mei, Andrews, Genevieve A., Frederick, Mitchell J., Galer, Chad, Milas, Zvonimir L., Morrow, Phuong Khanh H., Myers, Jeffrey N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2958241/
https://ncbi.nlm.nih.gov/pubmed/20629091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hed.21455
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