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The Effect of Combination Anti-Endothelial Growth Factor Receptorr and Anti-Vascular Endgthelial Growth Factor Receptor 2 Targeted Therap on Lymph Node Metastasis: A Study in an Orthotopic Nude Mouse Model of Squamous Cell Carcinoma of the OralTongue
OBJECTIVE: To evaluate the therapeutic effect of treatment with a combination of the monoclonal antibodies to the VEGFR (DC101) and the EGFR (cetuximab) in an orthotopic nude mouse model of metastatic squamous cell carcinoma of oral tongue (SCCOT). DESIGN: In vivo study. SUBJECTS: 8- to 12- week-old...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2914603/ https://ncbi.nlm.nih.gov/pubmed/19380367 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archoto.2009.14 |
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