The Effect of Combination Anti-Endothelial Growth Factor Receptorr and Anti-Vascular Endgthelial Growth Factor Receptor 2 Targeted Therap on Lymph Node Metastasis: A Study in an Orthotopic Nude Mouse Model of Squamous Cell Carcinoma of the OralTongue

OBJECTIVE: To evaluate the therapeutic effect of treatment with a combination of the monoclonal antibodies to the VEGFR (DC101) and the EGFR (cetuximab) in an orthotopic nude mouse model of metastatic squamous cell carcinoma of oral tongue (SCCOT). DESIGN: In vivo study. SUBJECTS: 8- to 12- week-old...

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Main Authors: Sano, Daisuke, Choi, Sungweon, Milas, Zvonimir Luka, Zhou, Ge, Galer, Chad E., Su, Ying-Wen, Gule, Maria, Zhao, Mei, Zhu, Zhenping, Myers, Jeffrey N.
格式: Artigo
語言:Inglês
出版: 2009
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914603/
https://ncbi.nlm.nih.gov/pubmed/19380367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/archoto.2009.14
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