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Stromal Metalloproteinase-9 Is Essential to Angiogenesis and Progressive Growth of Orthotopic Human Pancreatic Cancer in Parabiont Nude Mice

We determined whether host matrix metalloproteinase (MMP) 9 is essential to angiogenesis and to the growth of L3.6pl human pancreatic cancer cells implanted into the pancreas of wild-type (MMP-9(+/+)) and knockout (MMP-9(-/-)) nude mice. Four weeks after tumor cell injection, pancreatic tumors in MM...

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Detalhes bibliográficos
Main Authors: Nakamura, Toru, Kuwai, Toshio, Kim, Jang-Seong, Fan, Dominic, Kim, Sun-Jin, Fidler, Isaiah J
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2077889/
https://ncbi.nlm.nih.gov/pubmed/18030366
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