CETUXIMAB AND IRINOTECAN INTERACT SYNERGISTICALLY TO INHIBIT THE GROWTH OF ORTHOTOPIC ANAPLASTIC THYROID CARCINOMA XENOGRAFTS IN NUDE MICE

OBJECTIVE: Anaplastic thyroid carcinoma (ATC) remains one of the most lethal known human cancers. Targeted molecular therapy with cetuximab, a monoclonal antibody against EGFR, offers new treatment potentials for patient with ATC. Cetuximab has also been reported to have synergistic effects when com...

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Bibliographic Details
Main Authors: Kim, Seungwon, Prichard, Christopher N., Younes, Maher N., Yazici, Yasemin D., Jasser, Samar A., Bekele, B. Nebiyou, Myers, Jeffrey N.
Format: Artigo
Language:Inglês
Published: 2006
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1403833/
https://ncbi.nlm.nih.gov/pubmed/16428506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-05-1325
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