Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice

BACKGROUND: VA7 is a neurotropic alphavirus vector based on an attenuated strain of Semliki Forest virus. We have previously shown that VA7 exhibits oncolytic activity against human melanoma xenografts in immunodeficient mice. The purpose of this study was to determine if intravenously administered...

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書誌詳細
主要な著者: Heikkilä, Jari E., Vähä-Koskela, Markus J. V., Ruotsalainen, Janne J., Martikainen, Miika W., Stanford, Marianne M., McCart, J. Andrea, Bell, John C., Hinkkanen, Ari E.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2010
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799335/
https://ncbi.nlm.nih.gov/pubmed/20066051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008603
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