Intravenously Administered Alphavirus Vector VA7 Eradicates Orthotopic Human Glioma Xenografts in Nude Mice

BACKGROUND: VA7 is a neurotropic alphavirus vector based on an attenuated strain of Semliki Forest virus. We have previously shown that VA7 exhibits oncolytic activity against human melanoma xenografts in immunodeficient mice. The purpose of this study was to determine if intravenously administered...

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Bibliografski detalji
Glavni autori: Heikkilä, Jari E., Vähä-Koskela, Markus J. V., Ruotsalainen, Janne J., Martikainen, Miika W., Stanford, Marianne M., McCart, J. Andrea, Bell, John C., Hinkkanen, Ari E.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799335/
https://ncbi.nlm.nih.gov/pubmed/20066051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008603
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