Interferon-β Sensitivity of Tumor Cells Correlates With Poor Response to VA7 Virotherapy in Mouse Glioma Models

In our recent study, replicative alphaviral vector VA7 was found to be effective against orthotopic human U87-glioma xenografts in an athymic mouse model eradicating the tumors with single intravenous (i.v.) injection. Here, we tested the efficacy of VA7 in immunocompetent orthotopic GL261 and CT-2A...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ruotsalainen, Janne, Martikainen, Miika, Niittykoski, Minna, Huhtala, Tuulia, Aaltonen, Tytti, Heikkilä, Jari, Bell, John, Vähä-Koskela, Markus, Hinkkanen, Ari
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2012
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412495/
https://ncbi.nlm.nih.gov/pubmed/22434140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.53
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires