Oncolytic alphavirus SFV-VA7 efficiently eradicates subcutaneous and orthotopic human prostate tumours in mice

BACKGROUND: Despite recent therapeutic and diagnostic advances, prostate cancer remains the second leading cause of cancer-related deaths among men in the Western world. Oncolytic viruses that replicate selectively in tumour cells represent a novel treatment candidate for these malignancies. METHODS...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Cancer
Prif Awduron: Martikainen, Miika, Ruotsalainen, Janne, Tuomela, Johanna, Härkönen, Pirkko, Essand, Magnus, Heikkilä, Jari, Hinkkanen, Ari
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Translational Therapeutics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520213/
https://ncbi.nlm.nih.gov/pubmed/28557974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.151
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