MicroRNA-Attenuated Clone of Virulent Semliki Forest Virus Overcomes Antiviral Type I Interferon in Resistant Mouse CT-2A Glioma

Glioblastoma is a terminal disease with no effective treatment currently available. Among the new therapy candidates are oncolytic viruses capable of selectively replicating in cancer cells, causing tumor lysis and inducing adaptive immune responses against the tumor. However, tumor antiviral respon...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Martikainen, Miika, Niittykoski, Minna, von und zu Fraunberg, Mikael, Immonen, Arto, Koponen, Susanna, van Geenen, Maartje, Vähä-Koskela, Markus, Ylösmäki, Erkko, Jääskeläinen, Juha E., Saksela, Kalle, Hinkkanen, Ari
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4580204/
https://ncbi.nlm.nih.gov/pubmed/26269187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01868-15
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