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Attenuation of Semliki Forest Virus Neurovirulence by MicroRNA-Mediated Detargeting

Artificial target sequences for tissue-specific miRNAs have recently been introduced as a new means for altering the tissue tropism of viral replication. This approach can be used to improve the safety of oncolytic viruses for cancer virotherapy by restricting their replication in unwanted tissues,...

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Bibliografische gegevens
Hoofdauteurs: Ylösmäki, Erkko, Martikainen, Miika, Hinkkanen, Ari, Saksela, Kalle
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536368/
https://ncbi.nlm.nih.gov/pubmed/23077310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01940-12
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