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Replicase Complex Genes of Semliki Forest Virus Confer Lethal Neurovirulence

Semliki Forest virus (SFV) is a mosquito-transmitted pathogen of small rodents, and infection of adult mice with SFV4, a neurovirulent strain of SFV, leads to lethal encephalitis in a few days, whereas mice infected with the avirulent A7(74) strain remain asymptomatic. In adult neurons, A7(74) is un...

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Bibliografiske detaljer
Main Authors: Tuittila, Minna T., Santagati, Maria G., Röyttä, Matias, Määttä, Jorma A., Hinkkanen, Ari E.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111978/
https://ncbi.nlm.nih.gov/pubmed/10775594
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