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Alphavirus Replicase Protein NSP1 Induces Filopodia and Rearrangement of Actin Filaments

Expression of the NSP1 protein of Semliki Forest virus and Sindbis virus in cultured cells induced filopodia-like extensions containing NSP1 but not F actin. The actin stress fibers disappeared, whereas vimentin, keratin, and tubulin networks remained intact. The effects of NSP1 were dependent on it...

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Main Authors: Laakkonen, Pirjo, Auvinen, Petri, Kujala, Pekka, Kääriäinen, Leevi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1998
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC110611/
https://ncbi.nlm.nih.gov/pubmed/9811773
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