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Alphavirus Replicase Protein NSP1 Induces Filopodia and Rearrangement of Actin Filaments

Expression of the NSP1 protein of Semliki Forest virus and Sindbis virus in cultured cells induced filopodia-like extensions containing NSP1 but not F actin. The actin stress fibers disappeared, whereas vimentin, keratin, and tubulin networks remained intact. The effects of NSP1 were dependent on it...

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Bibliographic Details
Published in:J Virol
Main Authors: Laakkonen, Pirjo, Auvinen, Petri, Kujala, Pekka, Kääriäinen, Leevi
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110611/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.10265-10269.1998
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