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Attenuation of Semliki Forest Virus Neurovirulence by MicroRNA-Mediated Detargeting

Artificial target sequences for tissue-specific miRNAs have recently been introduced as a new means for altering the tissue tropism of viral replication. This approach can be used to improve the safety of oncolytic viruses for cancer virotherapy by restricting their replication in unwanted tissues,...

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Sonraí Bibleagrafaíochta
Main Authors: Ylösmäki, Erkko, Martikainen, Miika, Hinkkanen, Ari, Saksela, Kalle
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3536368/
https://ncbi.nlm.nih.gov/pubmed/23077310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01940-12
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