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Attenuation of Semliki Forest Virus Neurovirulence by MicroRNA-Mediated Detargeting
Artificial target sequences for tissue-specific miRNAs have recently been introduced as a new means for altering the tissue tropism of viral replication. This approach can be used to improve the safety of oncolytic viruses for cancer virotherapy by restricting their replication in unwanted tissues,...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3536368/ https://ncbi.nlm.nih.gov/pubmed/23077310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01940-12 |
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