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MicroRNA-Detargeted Mengovirus for Oncolytic Virotherapy
Mengovirus, a member of the Picornaviridae family, has a broad cell tropism and can cause encephalitis and myocarditis in multiple mammalian species. Attenuation has been achieved by shortening the polycytidine tract in the 5′ noncoding region (NCR). A poly(C)-truncated strain of mengovirus, vMC(24)...
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Publicado no: | J Virol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4810567/ https://ncbi.nlm.nih.gov/pubmed/26865716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02810-15 |
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