Immunohistochemical Characterization and Sensitivity to Human Adenovirus Serotypes 3, 5, and 11p of New Cell Lines Derived from Human Diffuse Grade II to IV Gliomas

BACKGROUND: Oncolytic adenoviruses show promise in targeting gliomas because they do not replicate in normal brain cells. However, clinical responses occur only in a subset of patients. One explanation could be the heterogenic expression level of virus receptors. Another contributing factor could be...

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Publicado no:Transl Oncol
Main Authors: Niittykoski, Minna, von und zu Fraunberg, Mikael, Martikainen, Miika, Rauramaa, Tuomas, Immonen, Arto, Koponen, Susanna, Leinonen, Ville, Vähä-Koskela, Markus, Zhang, Qiwei, Kühnel, Florian, Mei, Ya-Fang, Ylä-Herttuala, Seppo, Jääskeläinen, Juha E., Hinkkanen, Ari
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2017
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5610111/
https://ncbi.nlm.nih.gov/pubmed/28797937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2017.07.002
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