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Lacrimal Gland Development and Fgf10-Fgfr2b Signaling Are Controlled by 2-O- and 6-O-sulfated Heparan Sulfate

Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular signaling through its binding to various growth factors and receptors. In the lacrimal gland, branching morphogenesis depends on the interaction of heparan sulfate with Fgf10-Fg...

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Main Authors: Qu, Xiuxia, Carbe, Christian, Tao, Chenqi, Powers, Andrea, Lawrence, Roger, van Kuppevelt, Toin H., Cardoso, Wellington V., Grobe, Kay, Esko, Jeffrey D., Zhang, Xin
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2011
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077643/
https://ncbi.nlm.nih.gov/pubmed/21357686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225003
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