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Heparan Sulfate Domain Organization and Sulfation Modulate FGF-induced Cell Signaling

Heparan sulfates (HSs) modulate various developmental and homeostatic processes by binding to protein ligands. We have evaluated the structural characteristics of porcine HS in cellular signaling induced by basic fibroblast growth factor (FGF2), using CHO745 cells devoid of endogenous glycosaminogly...

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Detalhes bibliográficos
Main Authors: Jastrebova, Nadja, Vanwildemeersch, Maarten, Lindahl, Ulf, Spillmann, Dorothe
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930683/
https://ncbi.nlm.nih.gov/pubmed/20576609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093542
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