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Specific Heparan Sulfate Structures Modulate FGF10-mediated Submandibular Gland Epithelial Morphogenesis and Differentiation

FGF10, a heparan sulfate (HS)-binding growth factor, is required for branching morphogenesis of mouse submandibular glands (SMGs). HS increases the affinity of FGF10 for FGFR2b, which forms an FGF10·FGFR2b·HS ternary signaling complex, and results in diverse biological outcomes, including proliferat...

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書誌詳細
主要な著者: Patel, Vaishali N., Likar, Karen M., Zisman-Rozen, Simona, Cowherd, Samuel N., Lassiter, Keyonica S., Sher, Ifat, Yates, Edwin A., Turnbull, Jeremy E., Ron, Dina, Hoffman, Matthew P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2431040/
https://ncbi.nlm.nih.gov/pubmed/18230614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M709995200
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