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Lacrimal Gland Development and Fgf10-Fgfr2b Signaling Are Controlled by 2-O- and 6-O-sulfated Heparan Sulfate

Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular signaling through its binding to various growth factors and receptors. In the lacrimal gland, branching morphogenesis depends on the interaction of heparan sulfate with Fgf10-Fg...

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Detalhes bibliográficos
Main Authors: Qu, Xiuxia, Carbe, Christian, Tao, Chenqi, Powers, Andrea, Lawrence, Roger, van Kuppevelt, Toin H., Cardoso, Wellington V., Grobe, Kay, Esko, Jeffrey D., Zhang, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077643/
https://ncbi.nlm.nih.gov/pubmed/21357686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225003
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