Lacrimal Gland Development and Fgf10-Fgfr2b Signaling Are Controlled by 2-O- and 6-O-sulfated Heparan Sulfate

Heparan sulfate, an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular signaling through its binding to various growth factors and receptors. In the lacrimal gland, branching morphogenesis depends on the interaction of heparan sulfate with Fgf10-Fg...

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Main Authors: Qu, Xiuxia, Carbe, Christian, Tao, Chenqi, Powers, Andrea, Lawrence, Roger, van Kuppevelt, Toin H., Cardoso, Wellington V., Grobe, Kay, Esko, Jeffrey D., Zhang, Xin
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Glycobiology and Extracellular Matrices
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3077643/
https://ncbi.nlm.nih.gov/pubmed/21357686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225003
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