Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478

Blockade of epidermal growth factor receptor (EGFR) signaling with specific inhibitors of the EGFR tyrosine kinase retards cellular proliferation and arrests the growth of tumor xenografts. AG1478, an inhibitor of the EGFR tyrosine kinase, is used in laboratory studies; however, its therapeutic pote...

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Hlavní autoři: Johns, Terrance G., Luwor, Rodney B., Murone, Carmel, Walker, Francesca, Weinstock, Janet, Vitali, Angela A., Perera, Rushika M., Jungbluth, Achim A., Stockert, Elisabeth, Old, Lloyd J., Nice, Edouard C., Burgess, Antony W., Scott, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2003
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC307660/
https://ncbi.nlm.nih.gov/pubmed/14676326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036503100
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