Antitumor efficacy of cytotoxic drugs and the monoclonal antibody 806 is enhanced by the EGF receptor inhibitor AG1478

Blockade of epidermal growth factor receptor (EGFR) signaling with specific inhibitors of the EGFR tyrosine kinase retards cellular proliferation and arrests the growth of tumor xenografts. AG1478, an inhibitor of the EGFR tyrosine kinase, is used in laboratory studies; however, its therapeutic pote...

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Main Authors: Johns, Terrance G., Luwor, Rodney B., Murone, Carmel, Walker, Francesca, Weinstock, Janet, Vitali, Angela A., Perera, Rushika M., Jungbluth, Achim A., Stockert, Elisabeth, Old, Lloyd J., Nice, Edouard C., Burgess, Antony W., Scott, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC307660/
https://ncbi.nlm.nih.gov/pubmed/14676326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2036503100
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