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New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres

Inhibition of the epidermal growth factor receptor (EGFR) has been shown to reduce tumor growth and metastases and promote axon regeneration in the central nervous system. Current strategies for inhibiting EGFR include the administration of reversible or irreversible small-molecule tyrosine kinase i...

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Bibliografske podrobnosti
izdano v:J Microencapsul
Main Authors: Robinson, Rebecca, Bertram, James P., Reiter, Jill L., Lavik, Erin B.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431618/
https://ncbi.nlm.nih.gov/pubmed/20055747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02652040903131285
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