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New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres

Inhibition of the epidermal growth factor receptor (EGFR) has been shown to reduce tumor growth and metastases and promote axon regeneration in the central nervous system. Current strategies for inhibiting EGFR include the administration of reversible or irreversible small-molecule tyrosine kinase i...

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Detalhes bibliográficos
Publicado no:J Microencapsul
Main Authors: Robinson, Rebecca, Bertram, James P., Reiter, Jill L., Lavik, Erin B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431618/
https://ncbi.nlm.nih.gov/pubmed/20055747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02652040903131285
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