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New platform for controlled and sustained delivery of the EGF receptor tyrosine kinase inhibitor AG1478 using poly(lactic-co-glycolic acid) microspheres

Inhibition of the epidermal growth factor receptor (EGFR) has been shown to reduce tumor growth and metastases and promote axon regeneration in the central nervous system. Current strategies for inhibiting EGFR include the administration of reversible or irreversible small-molecule tyrosine kinase i...

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Pubblicato in:J Microencapsul
Autori principali: Robinson, Rebecca, Bertram, James P., Reiter, Jill L., Lavik, Erin B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431618/
https://ncbi.nlm.nih.gov/pubmed/20055747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/02652040903131285
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