The EGFR tyrosine kinase inhibitor tyrphostin AG-1478 causes hypomagnesemia and cardiac dysfunction

We determined whether the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) N-(3-chlorophenyl)-6,7-dimethoxy-4-quinazolinamine (tyrphostin AG-1478) causes hypomagnesemia and cardiac dysfunction in rats. Tyrphostin was administered (3 times per week, intraperitoneal injection, t...

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Bibliographic Details
Main Authors: Weglicki, William B., Kramer, Jay H., Spurney, Christopher F., Chmielinska, Joanna J., Mak, I. Tong
Format: Artigo
Language:Inglês
Published: 2012
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3734545/
https://ncbi.nlm.nih.gov/pubmed/22646904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/y2012-023
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