Loss of neutral endopeptidase activity contributes to neutrophil activation and cardiac dysfunction during chronic hypomagnesemia: Protection by substance P receptor blockade

BACKGROUND/OBJECTIVE: Hypomagnesemia (Hypo-Mg) in rodents leads to neurogenic inflammation associated with substance P (SP) elevations; neutral endopeptidase (NEP) is a principle cell surface proteolytic enzyme, which degrades SP. The effects of chronic Hypo-Mg on neutrophil NEP activity, cell activ...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Mak, I Tong, Chmielinska, Joanna J, Kramer, Jay H, Spurney, Christopher F, Weglicki, William B
Materialtyp: Artigo
Språk:Inglês
Publicerad: Pulsus Group Inc 2011
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3206104/
https://ncbi.nlm.nih.gov/pubmed/22131854
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk