Mg supplementation attenuates ritonavir-induced hyperlipidemia, oxidative stress, and cardiac dysfunction in rats

Use of protease inhibitors (PI) in HIV patients is associated with hyperlipidemia and increased risk of coronary heart disease. Chronic systemic and cardiac effects of ritonavir (RTV), a universal PI booster, and Mg supplementation were examined. RTV was administered (75 mg·kg(−1)·day(−1) po) to Lew...

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Detalhes bibliográficos
Main Authors: Mak, I. Tong, Kramer, Jay H., Chen, Xi, Chmielinska, Joanna J., Spurney, Christopher F., Weglicki, William B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2013
Assuntos:
Translational Physiology Call for Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841797/
https://ncbi.nlm.nih.gov/pubmed/24049113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00268.2013
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