Mg supplementation attenuates ritonavir-induced hyperlipidemia, oxidative stress, and cardiac dysfunction in rats

Use of protease inhibitors (PI) in HIV patients is associated with hyperlipidemia and increased risk of coronary heart disease. Chronic systemic and cardiac effects of ritonavir (RTV), a universal PI booster, and Mg supplementation were examined. RTV was administered (75 mg·kg(−1)·day(−1) po) to Lew...

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Hlavní autoři: Mak, I. Tong, Kramer, Jay H., Chen, Xi, Chmielinska, Joanna J., Spurney, Christopher F., Weglicki, William B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Translational Physiology Call for Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841797/
https://ncbi.nlm.nih.gov/pubmed/24049113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00268.2013
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