Mg supplementation attenuates ritonavir-induced hyperlipidemia, oxidative stress, and cardiac dysfunction in rats

Use of protease inhibitors (PI) in HIV patients is associated with hyperlipidemia and increased risk of coronary heart disease. Chronic systemic and cardiac effects of ritonavir (RTV), a universal PI booster, and Mg supplementation were examined. RTV was administered (75 mg·kg(−1)·day(−1) po) to Lew...

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Autores principales: Mak, I. Tong, Kramer, Jay H., Chen, Xi, Chmielinska, Joanna J., Spurney, Christopher F., Weglicki, William B.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2013
Materias:
Translational Physiology Call for Papers
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3841797/
https://ncbi.nlm.nih.gov/pubmed/24049113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00268.2013
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