Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

Hepatitis C virus (HCV) RNA replication depends on viral protein association with intracellular membranes, but the influence of membrane composition on viral replication is unclear. We report that HCV RNA replication and assembly of the viral replication complex require geranylgeranylation of one or...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Ye, Jin, Wang, Chunfu, Sumpter, Rhea, Brown, Michael S., Goldstein, Joseph L., Gale, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2003
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307659/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14668447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2237238100
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