Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation

Hepatitis C virus (HCV) RNA replication depends on viral protein association with intracellular membranes, but the influence of membrane composition on viral replication is unclear. We report that HCV RNA replication and assembly of the viral replication complex require geranylgeranylation of one or...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Ye, Jin, Wang, Chunfu, Sumpter, Rhea, Brown, Michael S., Goldstein, Joseph L., Gale, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307659/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14668447/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2237238100
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