Disruption of hepatitis C virus RNA replication through inhibition of host protein geranylgeranylation
Hepatitis C virus (HCV) RNA replication depends on viral protein association with intracellular membranes, but the influence of membrane composition on viral replication is unclear. We report that HCV RNA replication and assembly of the viral replication complex require geranylgeranylation of one or...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC307659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14668447/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2237238100 |
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