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Inhibition of EGFR-STAT3 signaling with erlotinib prevents carcinogenesis in a chemically-induced mouse model of oral squamous cell carcinoma

Chemoprevention of head and neck squamous cell carcinoma (HNSCC), a disease associated with high mortality rates and frequent occurrence of second primary tumor (SPT), is an important clinical goal. The epidermal growth factor receptor (EGFR)-signal transducer and activator of transcription (STAT)-3...

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書誌詳細
主要な著者: Leeman-Neill, Rebecca J., Seethala, Raja R., Singh, Shivendra V., Freilino, Maria L., Bednash, Joseph S., Thomas, Sufi M., Panahandeh, Mary C., Gooding, William E., Joyce, Sonali C., Lingen, Mark W., Neill, Daniel B., Grandis, Jennifer R.
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076320/
https://ncbi.nlm.nih.gov/pubmed/21163936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-10-0249
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