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Guggulsterone enhances head and neck cancer therapies via inhibition of signal transducer and activator of transcription-3
Treatment of human head and neck squamous cell carcinoma (HNSCC) cell lines with guggulsterone, a widely available, well-tolerated nutraceutical, demonstrated dose-dependent decreases in cell viability with EC(50)s ranging from 5 to 8 μM. Guggulsterone induced apoptosis and cell cycle arrest, inhibi...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783003/ https://ncbi.nlm.nih.gov/pubmed/19762335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp211 |
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