Combined Targeting of Epidermal Growth Factor Receptor, Signal Transducer and Activator of Transcription-3, and Bcl-X(L) Enhances Antitumor Effects in Squamous Cell Carcinoma of the Head and Neck

Squamous cell carcinoma of the head and neck (SCCHN) is a leading cause of cancer deaths worldwide. Epidermal growth factor receptor (EGFR), an upstream mediator of signal transducer and activator of transcription (STAT)-3 is overexpressed in a variety of cancers, including SCCHN. Therapies such as...

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Bibliografiska uppgifter
Huvudupphovsmän: Boehm, Amanda L., Sen, Malabika, Seethala, Raja, Gooding, William E., Freilino, Maria, Yan Wong, Silvia Man, Wang, Shaomeng, Johnson, Daniel E., Grandis, Jennifer Rubin
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437602/
https://ncbi.nlm.nih.gov/pubmed/18326051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.107.044636
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