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Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer

The contribution of the stromal microenvironment to the progression of endometrial cancer (EC) has not been well explored. We have conditionally expressed a mutant allele of adenomatous polyposis coli (APC(cKO)) in murine uterine stroma cells to study its effect on uterine development and function....

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Détails bibliographiques
Auteurs principaux: Tanwar, Pradeep S., Zhang, LiHua, Roberts, Drucilla J., Teixeira, Jose M.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3076144/
https://ncbi.nlm.nih.gov/pubmed/21363919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-3166
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