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Cables1 is a tumor suppressor gene that regulates intestinal tumor progression in Apc(Min) mice
The transformation of colonic mucosal epithelium to adenocarcinoma requires progressive oncogene activation and tumor suppressor gene inactivation. Loss of chromosome 18q is common in colon cancer but not in precancerous adenomas. A few candidate tumor suppressor genes have been identified in this r...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Landes Bioscience
2013
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3742496/ https://ncbi.nlm.nih.gov/pubmed/23792637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.25089 |
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