Constitutive Activation of Beta-Catenin in Uterine Stroma and Smooth Muscle Leads to the Development of Mesenchymal Tumors in Mice

Leiomyomas and other mesenchymally derived tumors are the most common neoplasms of the female reproductive tract. Presently, very little is known about the etiology and progression of these tumors, which are the primary indication for hysterectomies. Dysregulated WNT signaling through beta-catenin i...

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Hlavní autoři: Tanwar, Pradeep S., Lee, Ho-Joon, Zhang, LiHua, Zukerberg, Lawrence R., Taketo, Makoto M., Rueda, Bo R., Teixeira, Jose M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for the Study of Reproduction, Inc. 2009
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2731978/
https://ncbi.nlm.nih.gov/pubmed/19403928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.108.075648
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