The Müllerian inhibiting substance type 2 receptor suppresses tumorigenesis in testes with sustained β-catenin signaling

Dysregulated WNT/β-catenin signaling in murine testes results in a phenotype with complete germ cell loss that resembles human Sertoli cell-only syndrome. In other systems, including the ovary, dysregulated WNT/β-catenin induces tumorigenesis but no tumors are observed in the mutant testes without d...

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Hauptverfasser: Tanwar, Pradeep S., Commandeur, Arno E., Zhang, LiHua, Taketo, Makoto M., Teixeira, Jose M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2012
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Original Manuscript
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3510735/
https://ncbi.nlm.nih.gov/pubmed/22962306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs281
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